Glycerophosphate acid is an organic compound formed by dehydration of glycerol and phosphoric acid. Its chemical formula is C3H9O6P and molecular weight is 172.08.
Glycerophosphate acid
CAS number: 57-03-4
English name: Glycerophophoric acid
Synonyms in English: glycol-3 phase; SN glycol-3 phase; PHOSPHATIDYLGLYCEROL; EGGPHOSPHATIDYLGLYCEROL; 2,3-hydroxy-1-copyldihydrogenphase; 1,2,3-Paranetriol, 1- (dihydrophenolChemicalbookphase); EGGPE; GLYCEROL-3P; Glycerol-3-P; CompoundC749
Chinese name: Glycerol phosphate ester
Chinese synonym: glycerophosphate; Phosphatidyl glycerol; Glycerol phosphate ester; Α- Glycerol phosphate; Phosphatidyl glyceride; Phosphatidyl glyceride; Glycerol phosphate 1G; Compound C749; 2,3-dihydroxypropyl phosphate dihydrogen salt; 2,3-dihydroxypropyl phosphate dihydrogen ester
Molecular formula: C3H9O6P
Molecular weight: 172.07
EINECS number: 200-307-1
Mol file: 57-03-4.mol
Glycerol phosphate properties
Melting point -25 ° C
Boiling point 485.5 ± 55.0 ° C (Predicted)
Density 1.738 ± 0.06g/cm3 (Predicted)
Storage conditions -20-0 ° C
Acidity coefficient (pKa) 1.84 ± 0Chemicalbook.10 (Predicted)
CAS Database 57-03-4
EPA Chemical Information 1,2,3-Propanethriol, 1- (dihydrogen phase) (57-03-4)
Application and synthesis method of glycerol phosphate ester
Usage:
Glycerol phosphate, also known as phosphoglycerol, can be used to analyze skeletal muscles from vigorous exercise to before and after fatigue.
Synthesis method:
Take glycerol (0.5mol) in an ice bath, add POCl3 (0.6mol) and product A (based on the molar amount of pyrophosphate, product ChemicalbookA containing 1mmol of pyrophosphate) to glycerol, naturally recover to room temperature, stir for 6 hours, and then perform vacuum distillation to collect the glycerol phosphate ester fraction (80.62g, yield 93.7%). The structural confirmation data is consistent with known reports. Additionally, HPLC analysis shows that the glycerol phosphate ester is pure α Glycerol phosphate ester, free of β Type by-products.